Non-canonical Wnt signalling and regulation of gastrulation movements.

نویسندگان

  • Masazumi Tada
  • Miguel L Concha
  • Carl Philipp Heisenberg
چکیده

Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements.

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عنوان ژورنال:
  • Seminars in cell & developmental biology

دوره 13 3  شماره 

صفحات  -

تاریخ انتشار 2002